What RAM (Memory) Is Compatible With My Motherboard?
X99 Motherboard, LGA 2011 Motherboard with 4 Channel DDR3 Memory Slots, M.2 Nvme NGFF Serial, ATA3.0 and ATA2.0 Ports, PCIe for I7.
What are PCIe x1 Slots Used For? - PC Guide 101
NVMe drives can generally be used in M.2 slots, but it is important to ensure compatibility with the specific M.2 slot on your motherboard.
NVMe vs. M.2: What’s the difference? | IBM
Answer: If your motherboard lacks NVMe support, you can add NVMe slots using PCIe Adapter cards or you can consider upgrading to a newer motherboard with NVMe slots to take advantage of NVMe SSDs.